Journal Articles and Book Chapters
2006 |
Jan L. Brandes.MD; David Kudrow, MD; Stuart R. Stark, MD; C. Phillip O’Carroll, MD; James U.Adelman, MD; Francis
J. O’Donnell, DO; W. James Alexander,MD, MPH; Susan Spruill, MS; Pamela S. Barrett,, PharmD; Shelly
E. Lener, PharmD. Sumatriptan / Naproxen Sodium for the Acute Treatment of Migraine: Superior Efficacy Compared with Monotherapy and Placebo. JAMA (in review, June 2006)
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20065 |
William P. Petros, Penelope J. Hopkins, Susan Spruill,
Gloria Broadwater, James J. Vredenburgh, O. Michael Colvin, William P.Peters, Roy B. Jones, Jeff Hall, and Jeffrey Marks,
2005.
Associations Between Drug Metabolism Genotypes, Chemotherapy Pharmacokinetics and Overall Survival in Patients With Breast
Cancer. J. Clininical Oncology. 23(25):6117-6125.
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2005 |
Timothy R. Smith, MD, Abraham Sunshine, MD, Stuart R. Stark, MD, Diane E. Littlefield, RN, MSN,
Susan E. Spruill,
MS, and W. James Alexander,
MD, MPH. 2005. Sumatriptan and Naproxen Sodium for Acute Treatment of Migraine. Headache.45:8(September):983-991.
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2002 |
Susan E. Spruill, Jun Lu, Sarah Hardy and Bruce Weir. 2002. Assessing Sources of Variability in Microarray Gene Expression Data. BioTechniques.
33(4):916-923.
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2001 |
Kenneth C. Mills, Susan
E. Spruill, Roy W. Kanne,
Katherine M. Parkman, and Ying Zhang, 2001. Tunnel Vision, Stimulants, Sedatives and Fatigue: Risk Factors for Driving and
Piloting, Human Factors. 43(2):310-327.
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2000 |
Lu, J., S. Hardy, W. Tao, S. Muse, B. Weir, and S. Spruill.
2001. Classical Statistical Approaches to Molecular Classification of Cancer From Gene Expression Profiling. Proceedings from the 1st Annual Critical Assessment of Microarray Data Analysis Conference (CAMDA’00).
Duke University, Durham, NC. December 18-19, 2000.
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1996 |
Colven, Christine E., Spruill,
Susan E., Bullard, Mary
Jo and Earnest Lori R. 1996. From Start to Finish in Record Time. Applied Clinical
Trials 5(4), 64-67.
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1996 |
Spruill, Susan E., Wilder, Lisa A. and Colven, Christine E. 1996. Selecting a CRO to Speed the Product to Market. Scrip Magazine, July/August
Issue 48, 18-19.
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1996 |
K.C. Mills, K.M. Parkman and S.E.
Spruill, 1996. A PC-Based
Software Test for Measuring Alcohol and Drug Effects in Human Subjects, Alcohol Clinic. Exp. Res., VOL 20:9,pp 1582-1591.
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1993 |
Shafer, S.R., R.A. Reinert, G. Eason, and S.E. Spruill.
1993. Analysis of ozone concentration - biomass response relationships among
open-pollinated families of loblolly pine. Can.
J. For. Res. 23:706-715.
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1993 |
Spruill, S.E.,
D. Richter, M.L. Gumpertz, J.O. Rawlings, and H.L Allen. 1993. Use of edaphic variables to control experimental error: A case
study on blocking and use of covariance. Soil Science 156(3):156-162.
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1993 |
Rawlings, John O. and Susan
E. Spruill. 1993. Combined
analysis of multi-experimental data to estimate polynomial and nonlinear mixed model regressions. In Case Studies in Biometry. Wiley and Sons.
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1992 |
Rawlings, J., and S.
Spruill. 1992. Response
model synthesis of the Southern Commercial Forest Research Data. Presented at the Air and Waste Management Conference
on Tropospheric Ozone and the Environment II: Effects, Modeling and Control and the Response of Southern Commercial Forest to Air Pollution. Atlanta, GA. Nov 4-7, 1991. Transaction
No. 21.
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1991 |
Heagle, Allen S., Michael R. McLaughlin, Joseph E. Miller, Ronald L. Joyner, and Susan E. Spruill. 1991. Adaptation of white clover population to chronic ozone stress. New
Phytol. 119:61-68.
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1991 |
Flagler, R., S. Spruill, A. Chappelka, T. Dean, L. Kress, and J. Reardon. 1992. Growth of three Southern pine species as affected by
acid rain and ozone. Presented at the Air and Waste Management Conference on Tropospheric Ozone and the Environment II: Effects,
Modeling and Control and the Response of Southern Commercial
Forest to Air Pollution. Atlanta,
GA. Nov 4-7, 1991. Transaction No. 21.
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1990 |
Lesser, V.M., J.O. Rawlings, S.E.
Spruill, and M.C. Somerville.
1990. Effects of ozone on agricultural crops: statistical methodologies and dose-response relationships.
Crop Science. 30:148-155.
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1989 |
Somerville, M.C., S.E. Spruill,
J.O. Rawlings, and V.M. Lesser. 1989. Impact of ozone and sulfur dioxide on yield of agricultural crops. NCARS Technical Bulletin
292, North Carolina State University, Raleigh, North
Carolina.
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1988 |
Spruill, S.E.,
V.M. Lesser, M.C. Somerville, and J.O. Rawlings. 1988. Methods
used for managing and analyzing the data stored in the NCLAN Data Library. Environmental Pollution - Special Issue:
Response of Crops to Air Pollutants 53(1-4):462-465.
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1985 |
Spruill, S.E.
and E.J. Eisen. 1985. Ovulation rate and embryo survival during gestation and the effects of ovariectomy on maternal nurturing
ability. J. Anim. Sci., 61(4):834-843.
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1984 |
Spruill, S.E.
and E.J. Eisen. 1984. Correlated response in fetal mortality during three phases of gestation in mice selected for large litters.
J. Anim. Sci., Abstr.
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1984 |
Spruill, S.E.
1984. Correlated responses in female reproductive traits in mice selected for increased litter size. Masters Thesis. North Carolina State University.
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Presentations
2006 |
Brandes, Jan L.; Kudrow, David; Stark, Stuart; O’Carroll, C. Phillip; Adelman, James U.; O’Donnell, Frank;
Spruill Susan; Alexander, W. James; Barrett, Pamela; Lener, Shelly. Superior Efficacy of Combination Therapy
over Monotherapy: Results of a Fixed Single-tablet Formulation of Sumatriptan Rt Techonology and Naproxen Sodium in the Acute
Treatment of Migraine in the Traditional Treatment Paradigm. Platform Presentation
at the 48th Annual Scientific Meeting of the American Headache Society. (June 2006)
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2005 |
J.R. Plachetka, S.E. Spruill, and W.J. Alexander. Baseline Nausea Status Influences Response to MT 100, But
Not Naproxen or Sumatriptan: Meta-Analysis Results From the MT 100 Development Program.
Poster Presentation at the 47th Annual Scientific Meeting of the American Headache Society. (June 2005)
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2005 |
J.R. Plachetka, S.E. Spruill, and W.J. Alexander. Patients Without Baseline Nausea Respond Best to MT 100 for
Pain Relief: Evidence For a Role of Dopamine in Migraine? Poster Presentation at the 47th Annual Scientific Meeting
of the American Headache Society. (June 2005)
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William Wargin, B.S. Pharm, Ph.D., Diane Littlefield, RN, MSN, Susan Spruill, MS, John R. Plachetka, Pharm.D.
The pharmacokinetic profile of dihydroergotamine from
MT 300Ô vs. DHE 45Ò.Poster Presentations at the
2003 American College of Clinical Pharmacy
Scientific Meeting (November 2003)
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Donna Gilbert,
Ph.D., Susan Spruill, MS, William Wargin, Ph.D., Diane Littlefield, RN, MSN, and John R. Plachetka, Pharm.D. Over-encapsulated ImitrexÒ 50 mg tablets are bioequivalent
to marketed Imitrex 50 mg tablets Poster Presentations at the 2003 American College of Clinical Pharmacy Scientific Meeting
(November 2003)
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Susan E. Spruill, M.S., Bill A. Wargin, Ph.D., Diane E. Littlefield, M.S.N., Leslie A. Davidson, Pharm.D., John R. Plachetka, Pharm.D. The Pharmacokinetics
and Bioavailability of Metoclopramide and Naproxen from MT 100Ô Tablets Poster Presentations at the 2003 American
College of Clinical Pharmacy Scientific Meeting (November 2003)
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Egilius Spierings, MD, Diane Littlefield, RN, MSN,
Julie Borland, B.Pharm., Susan Spruill, MS, John Plachetka,
Pharm. D. Tolerability profile of MT 100 during one year of treatment.
Poster Presentations at the XI Congress
of the International Headache Society (September 2003)
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Timothy
Smith, MD, Diane Littlefield, RN, MSN,
Jeannie Allen, BSN, Susan Spruill,
MS, John Plachetka, Pharm. D. MT 300 is an effective, well tolerated injectable antimigraine therapy. Poster Presentations at the XI Congress of the International Headache Society (September 2003)
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Richard
Pellegrino, MD, Diane Littlefield, RN, MSN, Julie
Borland, B.Pharm, Susan Spruill, MS, John
Plachetka, Pharm. D. Comparative efficacy of MT 100 and sumatriptan 50 mg in treating acute migraine subjects with severe
pain or nausea at baseline. Poster
Presentations at the XI Congress of the International Headache Society (September 2003)
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Ninan
Mathew, MD, Susan E. Spruill, MS, Diane E. Littlefield, RN, MSN, Alison C. Lyke, PharmD, John R. Plachetka, PharmD Time course
of symptom relief with various anti-migraine therapies. Poster Presentations
at the XI Congress of the International Headache Society (September 2003)
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Egilius L.H.
Spierings, PhD, Susan E. Spruill, MS, Gemma Matthys, CCRA, Diane Littlefield, RN, MSN, and John R. Plachetka, PharmD Defining and analyzing
meaningful relief in clinical trials of acute migraine headache. Poster
Presentations at the 2003 AHS 45th Annual Scientific Meeting (June 2003)
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Benjamin M.
Frishberg, M.D., Diane Littlefield, RN, MSN, Jeannie Allen, BSN, Susan Spruill, MS, and John Plachetka, Pharm. D. A
new formulation of DHE is effective for sustaining relief in acute treatment of migraine. Poster Presentations at the 2003 AHS
45th Annual Scientific Meeting (June 2003)
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2001 |
Quinn, A.M. Guida, M., Shen, J. and Spruill, S. Predicting Regulatory Elements for Functional SNP Discovery. (2001)
TIGR 5th Annual Conference on Computational Genomics Program and Abstracts, pg 5.
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2001 |
Petros, W., Hopkins, P., Vredenburgh, J., Spruill, S.,
Broadwater, G., Colvin, M., Marks, J. and Hall, J. Associations Between Variants in Several Drug Metabolism Genes and Chemotherapy
Pharmacokinetics or Clinical Response. 2001. Presented at the 92nd
Annual AACR Meeting. New Orleans,
LA. March 24-28, 2001.
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2001 |
S. Spruill,
J. Lu, S. Hardy, M. Guida, B. Weir, S. Muse and J. Baker. Analysis of Microarray Data:
A Proof of Concept. 2001 Presented at the 2001 Spring Meeting for International Biometrics Society Eastern North American
Region. The Impact of Technology on Biometrics. Charlotte, NC. March 25-28, 2001.
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2000 |
Lu, J., S. Hardy, W. Tao, S. Muse, B. Weir, and S. Spruill.
2000. Classical Statistical Approaches to Molecular Classification of Cancer
From Gene Expression Profiling. Presented at the 1st Annual Critical Assessment
of Techniques for Microarray Data Analysis Conference (CAMDA’00). Duke University, Durham, NC.
December 18-19, 2000.
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1996 |
Atkinson, S., S. Spruill, S.E., Wakeford, C.W. 1996. Qualification Stage
for Enrichment Trials. Presented at the 9th Annual DIA Meeting on Statistical Issues in the Pharmaceutical Industry. Hilton
Head, SC March 31-April 2, 1996.
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1991 |
Spruill, S.E.,
and J.O. Rawlings. 1991. Effects of ozone and acid rain in southern pines after two years of exposure and comparison
to earlier results. Presented at the Annual Meeting of the Southern Commercial
Forest Research Cooperative. Clemson, SC. May 13-15, 1991.
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1991 |
Mickler, Robert, and Susan
Spruill. 1991. An overview
of guidelines cooperating agencies should follow to insure data quality. Presented at the 1st Annual Meeting of the Southern
Global Change Program. Otto, NC. May 21-23, 1991.
|
1991 |
Rawlings, J. and S.
Spruill. 1991. Response
model synthesis of the Southern Commercial Forest Research Data. Presented at the Air and Waste Management Conference on Tropospheric
Ozone and the Environment II: Effects, Modeling and Control and the Response of Southern Commercial Forest to Air Pollution. Atlanta, GA. Nov 4-7, 1991.
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1991 |
Flagler, R., S. Spruill, A. Chappelka, T. Dean, L. Kress and J. Reardon.
1991. Growth of three Southern pine species as affected by acid rain and ozone. Presented at the Air and Waste Management
Conference on Tropospheric Ozone and the Environment II: Effects, Modeling and Control and the Response of Southern Commercial Forest
to Air Pollution. Atlanta, GA.
Nov 4-7, 1991.
|
1990 |
Flagler, R.B., and S.E.
Spruill. 1990. Regional
response of southern pines to acid rain and ozone. 11th North
American Forest Biology Workshop.
Athens, GA, June 1990.
|
1990 |
Spruill, Susan E. 1990. Analysis of the SCFRC intensive field experiments. Presented at the Annual Meeting of the Southern Commercial Forest
Research Cooperative. Auburn, AL. August 20-22, 1990.
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Technical Reports
1992 |
Spruill, Susan E., and John O. Rawlings. 1992. Four ways to create Gabriel's Biplots for graphic representation of principal component
analyses. North Carolina State University Institute of Statistics Mimeograph Series No. 2213.
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1992 |
Lieberman, Elliot, John Schakenbach, Doris A. Price, William Warren-Hicks, Susan E. Spruill, and Jane E. Mudano. 1992. Extended Relative
Accuracy Test Audits of SO2 and NOx Continuous Emissions Monitoring System at a Coal-Fired Power Plant.
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1992 |
Lieberman, Elliot, John Schakenbach, Doris A. Price, William Warren-Hicks, Susan E. Spruill, and Jane E. Mudano. 1992. Assessment
of Statistical Tests in 40 CFR 75.21 (FR, 12/3/91): Alternative Monitoring Systems.
|
1992 |
Spruill, Susan E. Using Unbiased Estimates of Variance and Standard Errors in the Precision
and Bias Tests for Alternative Monitoring Systems. Prepared for Elliot Lieberman
of Emissions Monitoring Division of the Acid Rain Division (July 15, 1992).
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1989 |
Shafer S., S. Spruill, and M. Somerville. 1989. Response of loblolly
pine seedlings to ozone and simulated acidic rain in controlled exposures: Results of studies conducted by the Southern Commercial
Forest Research Cooperative, 1986-1987. A Report to USFS/USDA.
|
1986 |
Eisen, E.J. and S.E.
Spruill. 1986. Selection
for large litter size can improve all of its components. 1986 Report of Department of Animal Science, North Carolina State University.
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1986 |
Lesser, V.M., J.O. Rawlings, S.E.
Spruill, and M.K. Nations.
1986. Data Synthesis and Analysis Program (SERCLAP). In: National Crop Loss Assessment Network (NCLAN) 1985 Annual Report,
W.W. Heck, et.al, pp. 193-222. Environmental Research Laboratory, Office of Research and Development, Corvallis, Oregon 97333
(EPA/600/3-87/031).
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